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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc6356bd7d385265d3a818f541c7af460ecd4e2e9c4ed5be32f5d3340e360d8f' 
  AND token = 'JNS7T/7CC+roXIcRKQ8BDEc5Ysj2B7mr2NsfLZr3ZUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}