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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8879fa19f2145cfe4e93b92f7b922ad00015b373f99a72832b4580bbc9cda2e7' 
  AND token = '4E2aVvjP5M2FH0RpVWELwAa+O4Kx7Rkjs41EbCMOTWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}