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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fefa4ac23f8d67439be69fee711486e23051f9be05b3245009aeb4488a9e47' 
  AND token = 'kUwcfr4/9mw/sjrj7hh/qTnctCJlhIoi2b62+2XN8YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}