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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eccd3c5e66467c4bb4ce4cedc31c544342eb57d9e27bff1088a80ec4a69d04f4' 
  AND token = 'smSQSVW0vKLg8uLMVWXbgbZcoddVtAkLs4z+oekC8ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}