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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e0546b9d63e44dd632b3ec8186d8cc2fbd0ad1ac35c969cf4a9561cca32c5d' 
  AND token = 'MzxmBV3Y0AoRElNoRVJrE0RDN8eYesiLH3TzS578Xgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}