SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c5b9aabf7225db3f696e5a882604cc52e74f70b8dbd6c5a1ba4dbc0be5aed4' 
  AND token = 'U4hRNIgDIrpiDy5dovRNEDxf3Vzv6QNf7LpJFD2/YvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}