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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b358343db6cadc8ce3e0e8a977b4faf878f81b35b2a83fccdd54a7f61a3d9916' 
  AND token = 'ju3l9HDYnzrQ23nGCX0ZXr3LaIYL6NYOKWpNPhkI6V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}