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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269b11e23d1a6d5c3044b0933567ccea65bda97768520f77c993108afd7f8e2f' 
  AND token = 'Zq+bTINQuqV+Ag0VR9Ju9vNQEgWpWnqWz3AD6IINijo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}