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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6344c9d0b8bfe88e3594943d7c78b3da17e0f3f1dd4b4271406d04d6091540b1' 
  AND token = '0iYUTy3OfEy9xgEMNUdWhooKzjeWFeL+6HN0QRYrQGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}