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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ea12160f7ed445d05234aaa934c8da03aa6da74b63ccbfd8b36068068daf82' 
  AND token = 'rC7AtCxYCQ6rXVgyiJAYGrQz5bY4iKhTJFeCzGlx5cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}