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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21278e0407cf79c0800ecda76e0bc725c18341e69095c34700bce8e81c8192ff' 
  AND token = 'tOVrAJJBLblhv8+bWq7Bbfe0Z8In85BXXu3BaWE/0PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}