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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eac58ba912a737a9dec07b16aff05e451db1ccb3f18f12c106a1be3859667dc' 
  AND token = '4QwsEoGbBkzhYPnqoptHDY/kzGhLbW5MoTwVocmsr3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}