SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c213dc00428bc16b4ccbb93a41ecce4eb717e169fb8555067b1147f7bf9bfaef' 
  AND token = 'wgz3ZRl2wYxFEcd4SMjAdDLXAy1dYbrEioRKrOm+HcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}