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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e13eaf0bacf7219d5407784b18d10100b94d5daffeef8ebc404c1bb29dd1403' 
  AND token = 'IaA01enPV/BDVTsIVh3okTgz+t+r6yGFOymx/id4K/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}