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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851c08003727296ccbe62010e2701b3e599879d78d59a84583270676cad2284e' 
  AND token = 'zis0QQPfsLqDAqkk0G2b/G6HDeNy9IH0SoKmzlXUGD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}