SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4d6edac638ac7095cb2c36dd1ddc78faffb242fb552ed63f893451270b4d93' 
  AND token = 'eDPfq53hgsQGc+LtQyBks+9uma6/dtWI4fI5XQ4FyO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}