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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf07793aebe4156d5b159bea0e7e662bfa4d61a22700240b710cc138a10c137' 
  AND token = 'GW5ysZJJ9+N7uYPJkeEGX2bxJeETnqU9F+vzBeV+20s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}