SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0aaa8f7660a348a5d85a82506231371709e10ade884bf8d505c347231e861c0' 
  AND token = 'udLeJ9RVyipR7W3vM9LpoQ2GibR2NoHR7JyyHpLXzQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}