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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a11545303f8bdda49e020fed29073a3c8e8fec63d7a43d9bfd1d3fd3dc56fc' 
  AND token = 'la00ZLESaweFowfkyDjPImw0PyDgL0Xx/pvj2hO0s0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}