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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a34fdca2dd6a1ac14f60096cb42e17d98c9002c6f232aabbafa5eae9652ddb' 
  AND token = 'irNJ+wePs0CfoHdFPXlhSPzvlZmTA3fUMTOwzmrTUqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}