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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce250187a748f8b89c05130b30e9177c1e7edf44d4ba3aee91b48dfb9f43399' 
  AND token = 'H9KNS2Td0HSc6XMw6BH3YugsBz+CEzi29W1n3pSO9xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}