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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6d0ce926245f39a796a65e9e1fbb09745f42458f67f33da179d54305e09c89' 
  AND token = 'nqkmD6GEhU2i8Iai6dXkuCEaYF4fB3wzTH4uWSBZWDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}