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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2676f5f255f4bfc0a1cc5023c730248b9275c25fef46a2859321dc65d21e25' 
  AND token = 'qpDzS3E/t4kXk6aPA0K5Gz3i7g0PXJE9LVFjGkTWNuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}