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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a208333212c15539982b8736a52a487890e5dc40d50805141911a3cab6a16e89' 
  AND token = 'jma+RuMFNfpLRiKSvkk3q8kWxYm58+4WXBlAU0F9Iac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}