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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0af7baa4806a586772bc3066a06bb6ec08fddd0baea2e4027b9fee81dce1084f' 
  AND token = 'uYmf15DsE+zaobT4DqMMuF/f/YfoHA/EroTsVZHcrGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}