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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1737e66c8b600d8926580fbf903670889c98a5e8449b8fe7bc9708869ac4c944' 
  AND token = 'rZPsKwr6B3QACb3C+Pt4/DDnGqKNgrc7MK4hFXRt8HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}