SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39d130324abf944c9f7e75ed7972d9b790e4e7f26e98a8efd584406723a2830' 
  AND token = 'XP/bJaPRlssVBluLT1MSclaHQZfHGItP5AgUy4uYcgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}