SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4606fa2f48366348fc4e79f488d189557516f27fb355b0f26e63db9e2cb171f' 
  AND token = 'KDxM83N3/n1ohF3eZidAm4xYZ7xs7rnf7/ZaeEOcwbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}