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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2ab9f256e2890685cf59bd007ba98cb87e9c63379fde9687379c8206b0aea0' 
  AND token = 'RTCvayKRAAjAQQ9zJAOf6CA/bpeDo+ov26fo9lgR+1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}