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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5a74b261374f20538b55d123736b245d6d6486e49da9cc2a99f4eb1133216b' 
  AND token = 'Cp+7zWFGXXoGqxnSYREGT7Xcc4ZCoZoc9BomqX1dteg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}