SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf8d18f4f84a1fe78c4a6ae9288e80493947c8233756cb9f5532844aca4c4663' 
  AND token = 'NFKI0EsvBkH4NZE5TNkimCmzD1rDlRY+2KI3EsvyY8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}