SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '831cdf53b960407c6263d36cda5ccf945af4c11cad38f84314481ffbf89e3488' 
  AND token = 'X1Rg8H23g7a1gLG9zUvYGNiphMW5dcTYtPsNvgq7yDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}