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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a5931e51513fe23bada20d82b1cc8a1958678f8d9fbb95278e40a3138b2050' 
  AND token = 'hvU0Xaf9WHmg7B5c8UnSPPo1lig3DszsBXgcNlW2PqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}