SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503a1b3a43689549cee934a880a35e9d76ae5e091ab5b9d17136264f8def3e9a' 
  AND token = 'xT/iFfGHW8Y4xghqZ4hDvfneK0Sut6SdRgq7/8Js27Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}