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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64b0545191dad5a920a08a1ee084e69a99507cf32f694b7d629e275ec410660' 
  AND token = '8V8pZ9/m8ViKGF6kgAAy2qWK1FsGf9wpbNEjdM/vV1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}