SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372bd507b92eb10466f82a107c2327a5db49a51d9dfcecd2d18dfdde3028b93b' 
  AND token = 'tmFgZIypFJ6JZil6Tp074SHSA4O2yMrfp5E9+RSGkE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}