SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd600d6902b4cb0f3e37e2c8818be06f793661cb5a23e1c36448344011bdb854' 
  AND token = 'kUlD8wrkE8UiMIJ4XJFQqpDmdSDaCMb1bqwf+d/Bx6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00097

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}