SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c64b8139ff8c7970d6b877b19c9fbeb2eec5ac05955b23f97aef982eb5247b' 
  AND token = 'gxA64stSxHFGxLtGkMtePmWKPzkbMWXSBo0mClqcd1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}