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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec8013fff466dc0b33f171f4d8ddfe4fe9995904ae6fec57c0124ee2bf3f14b' 
  AND token = 'DEFEo8BZZOYA0eR8sBnanjh7b4C5uYkszyIWS3B+o3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}