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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0159398e56cd40c29ae26f5da696c64e1e576b38139a6112f1e6116901fc487f' 
  AND token = 'W1S10TmNs7ijkCGN4PmL+IedSYgLox4yEXfDQnYzC6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}