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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4250ede123092fc5751a27ddcba12ad2965086c3efaa9dd5c868d92ebc2166' 
  AND token = 'jl1yIcn1UtHg3IzsFtS8ev1f6hlYwEHDuLWeJPgyLdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}