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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df57e83607dbe1b6b0a944386bc5e94069b76791b52797543dc2835d20c4155' 
  AND token = 'U7UWCIU+Uwrr+p1xPQzjIo6IjXzB2QRRvRI3jZa2rt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}