SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356900644923f460209244a5c1eef4cdbccacb63ecde4259cbc45d0e813d5046' 
  AND token = '50meFFqkUTqxBRAb4dssfBSkjF5YKy0r7hrFMaFYRD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}