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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ecfc35d7154729e6025b6e17745b8cc15c5daec462c159254f361bbd94c930' 
  AND token = 'wCZ1PTqhu0lMo7y7GS0BU5paCeOxkveQbZ9woJSYS9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}