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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a07a877ca32e0658c00c3d3cf9982106cc859ca0aa27b4b24d592420f41914' 
  AND token = 'VlwC9w8rLsuyv8XOYRyHbIi3LnM8nUQVPQxzbYn9mqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}