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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e8b27c00b1cf04fb8276ab988841ff1e102824126faa7cc39c5c02bf57ae02' 
  AND token = 'dq/Q8GvnmuLeO2noh5ZR6jZDop6dWyup7SKGX6m8WJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}