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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76e7372aa3b6c97ea6b89d3d40efa7d6e38eae22865cde3cce0229b502a6d96' 
  AND token = '+PDvHIvNOZsp7tUFnhUnLNOWyjRBvVY5RE5aOGJvE0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}