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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f96c37ac347438722f46f7f341ca02a431eab0608e39dcd9be8d0789b73f8c' 
  AND token = '8hoKDIV46mXgjls04SleYCGEwBYeusSacH4YPzE/pCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}