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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41609948ff79a9032ce9504d83c52ad37b747eb2caab80e453e8989bfcb6cf9' 
  AND token = 'zaPPyk/d+WNdhRtHaTsRtyI5kILP0Yaxhv6QNmW83N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}