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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fab4c22375b774213bdd8ed3a870443b2567fa4ca358e1db4ece5efb0facdec' 
  AND token = 'cXVJmYxXRwBwDfUaoAXCi8eMgoY7RsTBxW9ECdNy6Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}